Nonintubated Surfactant Application vs Conventional Therapy in Extremely Preterm Infants
نویسندگان
چکیده
منابع مشابه
Nonintubated Surfactant Application vs Conventional Therapy in Extremely Preterm Infants: A Randomized Clinical Trial.
IMPORTANCE Treatment of respiratory distress syndrome in premature infants with continuous positive airway pressure (CPAP) preserves surfactant and keeps the lung open but is insufficient in severe surfactant deficiency. Traditional surfactant administration is related to short periods of positive pressure ventilation and implies the risk of lung injury. CPAP with surfactant but without any pos...
متن کاملEarly CPAP versus Surfactant in Extremely Preterm Infants
BACKGROUND There are limited data to inform the choice between early treatment with continuous positive airway pressure (CPAP) and early surfactant treatment as the initial support for extremely-low-birth-weight infants. METHODS We performed a randomized, multicenter trial, with a 2-by-2 factorial design, involving infants who were born between 24 weeks 0 days and 27 weeks 6 days of gestation...
متن کاملSedation during Minimal Invasive Surfactant Therapy in Preterm Infants.
BACKGROUND There is no data available whether sedation should be given during minimally invasive surfactant therapy (MIST). OBJECTIVE To compare the level of comfort of preterm infants receiving sedation versus no sedation for MIST. METHODS A retrospective study of preterm infants receiving MIST was performed in Leiden University Medical Center in 2014. Sedation (propofol 1 mg/kg) was optio...
متن کاملOutcome trajectories in extremely preterm infants.
OBJECTIVE Methods are required to predict prognosis with changes in clinical course. Death or neurodevelopmental impairment in extremely premature neonates can be predicted at birth/admission to the ICU by considering gender, antenatal steroids, multiple birth, birth weight, and gestational age. Predictions may be improved by using additional information available later during the clinical cour...
متن کاملChorioamnionitis and outcome in extremely preterm infants.
INTRODUCTION Chorioamnionitis is a risk factor for preterm delivery. Intrauterine infection leads to the fetal inflammatory response which is characterised by elevated cytokine levels. Chorioamnionitis is reported to cause accelerated but abnormal lung maturation, resulting in decreased incidence of respiratory distress syndrome (RDS) but increased chronic lung disease (CLD), and predisposes th...
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ژورنال
عنوان ژورنال: JAMA Pediatrics
سال: 2015
ISSN: 2168-6203
DOI: 10.1001/jamapediatrics.2015.0504